Statement of Need
T-cell lymphomas (TCLs) are a biologically diverse group of diseases. Most patients afflicted with TCLs are diagnosed primarily with a subtype of nodal, peripheral TCL (PTCL) or extranodal, cutaneous TCL. Although PTCLs represent approximately 12%-15% of all non-Hodgkin lymphomas in Western populations, they are largely unexplored, and optimal treatment remains ill-defined due to the rarity and heterogeneity of the disease. Attempts to adapt treatment regimens commonly used for B-cell lymphomas have not shown a clinical benefit in most PTCL subtypes; 5-year survival rates remain at 15%-30%. Future clinical trials are needed that focus specifically on PTCL to advance our understanding of the disease and define optimal treatment modalities. Several new and promising therapeutic options have emerged within the past few years that are currently under investigation. At the conclusion of this activity, participants will know how to distinguish the various subtypes of PTCL, appreciate the barriers to definitive diagnosis, and evaluate current and novel treatment options for this disease.

Target Audience
This activity is intended for hematologists, oncologists, nurses, physician assistants, and other healthcare professionals interested in the latest advances in the treatment of patients with PTCL.

Educational Objectives
Upon completion of this activity, participants will be able to

1. Discuss the incidence, classification, and difficulty in reaching a definitive diagnosis of PTCL subtypes.
2. Evaluate current chemotherapy-based treatment options for patients with PTCL.
3. Assess the safety and efficacy of novel, therapeutic agents currently under investigation for the treatment of patients with PTCL.

Method of Participation
This interactive discussion/presentation will use multiple methods of participation to engage attendees and enhance the learning process.

Accreditation
Physicians: The CBCE™ (The Center for Biomedical Continuing Education) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The CBCE designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in this activity.

Physician Assistants: AAPA accepts certificates of participation for educational activities certified for Category 1 credit from AOACCME, Prescribed credit from AAFP, and AMA PRA Category 1 Credit™ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 1.0 hour of Category 1 credit for completing this program.

Nurses: The CBCE™ (The Center for Biomedical Continuing Education) is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

The CBCE designates this educational activity for 1.0 contact hour.

Accreditation by the American Nurses Credentialing Center’s Commission on Accreditation refers to recognition of educational activities and does not imply approval or endorsement of any product.

Certificate
The Evaluation and Request for Credit Form must be completed and returned to the CBCE following this activity to obtain credit. Please fill in the faculty name and date of the activity on the evaluation form. Participants will receive their certificate 4-6 weeks after the CBCE receives their form.

Acknowledgement of Commercial Support
The CBCE gratefully acknowledges the educational grant provided by Allos Therapeutics, Inc.

Americans with Disabilities Act
The CBCE fully complies with the legal requirements of the Americans with Disabilities Act and the rules and regulations thereof. If any participant in this educational activity is in need of support services, please notify the CBCE prior to the program.

Educational Inquiries
For further information, please contact the CBCE, 1707 Market Place Blvd., Suite 370, Irving, TX 75063; Phone: (877) 263-6911; Fax: (972) 929-8263; E-mail: localcme@thecbce.com.

Disclaimer
The content and views presented in this educational activity are those of the faculty and do not necessarily reflect the opinions or recommendations of the CBCE or Allos Therapeutics, Inc. This material has been prepared based on a review of multiple sources of information but is not comprehensive. Participants are advised to critically appraise the information presented, and they are encouraged to consult the available literature on any product or device mentioned in this program.